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Tuesday, July 21, 2020 | History

3 edition of Modulation of aging processes by dietary restriction found in the catalog.

Modulation of aging processes by dietary restriction

Modulation of aging processes by dietary restriction

  • 69 Want to read
  • 15 Currently reading

Published by CRC Press in Boca Raton .
Written in English

    Subjects:
  • Aging -- Nutritional aspects.,
  • Low-calorie diet.

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Byung Pal Yu.
    ContributionsYu, Byung Pal.
    Classifications
    LC ClassificationsQP86 .M66 1994
    The Physical Object
    Pagination281 p. :
    Number of Pages281
    ID Numbers
    Open LibraryOL1079011M
    ISBN 10084934994X
    LC Control Number94002316
    OCLC/WorldCa29702382

      A normal aging effect is a decline in extractable collagen from most connective tissues due to formation of cross-links between fibrils, and low food intake retards this aging effect in many laboratory animals. 19 Glycation of body proteins has been implicated in the aging process, and CR was found to reduce age-related accumulation of. Modulation of Age-Related Changes in Serum 1,Dihydroxyvitamin D and Parathyroid Hormone by Dietary Restriction of Fischer Rats Article (PDF Available) in Journal of Nutrition (11)

    And so this was looking at this process called dietary restriction, which is defined as the reduction of food and food intake without malnutrition. And this process has been shown to increase lifespan in every animal we’ve tested it in, whether it’s a single celled yeast, a fruit fly, a mouse, or actually a rhesus monkey, a non-human primate. Dietary Restriction Lipid Raft Dietary Cholesterol Dietary Lipid Membrane Cholesterol These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

      Protein restriction is much less difficult to maintain than dietary restriction and may be more powerful than dietary restriction in reducing the serum IGF-1 concentration in humans. Moreover, protein restriction, by lowering intracellular amino acid levels, reduces mTOR activity and stimulates autophagy, two key processes involved in aging and. Alterations in adipogenesis could have significant impact on several aging processes. We previously reported that calorie restriction (CR) in rats significantly increases the level of circulating.


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Modulation of aging processes by dietary restriction Download PDF EPUB FB2

Get this from a library. Modulation of aging processes by dietary restriction. [Byung Pal Yu;]. Modulation of aging processes by dietary restriction [] Yu, B.P. Access the full text The purpose of this book is to present to the reader the most salient and comprehensive information available on the action of dietary restriction on the Modulation of aging processes by dietary restriction book of aging by addressing its role in various physiological systems and pathologies Cited by: Recent research renders a better understanding of how reduced dietary intake extends the life span, supplying evidence that dietary restriction is a diverse and effective modulator of oxidative stress.

It has been proposed that this antioxidative mechanism is the underlying anti-aging action of dietary by:   His current research interests are in the areas of free radicals, lipid peroxidation, aging, and dietary restriction.

unique characteristics: (a) simplicity of implementa- tion; (b) reproducibility in effects; and (c) breadth of antiaging actions This review appraises DR, beginning with a brief history of its development into an anti-aging Cited by: The diet-restricted rodent model has been and is a major tool in experimental biogerontology.

A spectrum of findings indicates that dietary restriction retards the aging processes of mice and rats, the most salient of which is the increase in mortality rate doubling time. It also maintains many phys Cited by:   Dictionary of Terms • Aging: Aging is a biological process characterized by progressive decline in physiological function and structural integrity affected by intrinsic and extrinsic progressive deterioration in maintenance of homeostasis, broadly defined as aging, leads to increased risk of age-related diseases including type 2 diabetes, cardiovascular diseases, dementia.

Calorie restriction (CR), a nongenetic intervention that extends the lifespan of animals, also inhibits the GH-IGF-1 axis. That is the GH-IGF-1 paradox of aging. This chapter describes our current understanding of the signaling pathways that regulate aging and thus lifespan, particularly focusing on the GH-IGF-1 axis and its downstream signaling.

Nutrition modulation of human aging: The calorie restriction paradigm to reduce illness, disability and dependency during the aging process.

Interventions that have the potential to reduce disease risk and facilitate retention of health, productivity, independence, and quality of life through the aging years are therefore greatly sought. Protective effects of short-term dietary restriction in surgical stress and chemotherapy Sebastian Brandhorst, Eylul Harputlugil, James R.

Mitchell, Valter D. Longo Pages The nutritional modulation of the aging process which has provided a major breakthrough in the field of nutrition and longevity is also discussed. These include biomedical influences, and social and psychological aspects.

Section 3 includes dietary characteristics of the elderly population and methods for the assessment of nutritional status. Zhang M, Poplawski M, Yen K, Cheng H, Bloss E, Zhu X, Patel H, Mobbs CV () Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling.

PLoS Biol 7(11), e doi: / PubMed PubMedCentral CrossRef Google Scholar. ANTI-SENOINFLAMMATION OF CALORIE RESTRICTION (CR) CR that includes reduced calories but proper nutrition intake is the sole intervention known to date that can consistently delay biological aging process and extend both average and maximal lifespan ().Animal studies have documented that CR not only can increase lifespan, but also benefit other processes to promote.

Aging and oxidative stress: modulation by dietary restriction. Yu BP(1). Author information: (1)Department of Physiology, University of Texas Health Science Center, San AntonioUSA. Aging is an inevitable biological process that affects most living organisms.

Hadem IKH, Sharma R () Age- and tissue-dependent modulation of IGF-1/PI3K/Akt protein expression by dietary restriction in mice. Metab Res, Horm. doi: /s Google Scholar Haigis MC, Guarente LP () Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Rent or buy Modulation of Aging Processes by Dietary Restriction - GET EXCLUSIVE OFFERS.

Subscribe. MY ACCOUNT HELP DESK; Find Books. SHOPPING BAG (0) FREE SHIPPING. on all orders of $59 or more Modulation of Aging Processes by Dietary Restriction, by Yu, Byung Pal. Write a Review.

Note: Supplemental materials are not. In: Modulation of Aging Processes by Dietary Restriction. Yu BP, editor. Boca Raton, CRC Press Boca; pp.

1– McCay CM. The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutr. ; – Leto S, Kokkonen GC, Barrows CH. Dietary protein, life-span and biochemical variables in female mice.

Summary. Modulation of various aspects of oxidative stress by dietary restriction was reviewed. Recent evidence strongly supports the notion that dietary restriction is the most effective paradigm that can modulate free radical damage and provides the best test to generate evidence for the involvement of free radicals in the aging process.

Modulation of gene expression of SMP by LPS and calorie restriction during aging process. Exp Gerontol. ; – Lee DW, Yu BP. Modulation of free radicals and superoxide dismutases by age and dietary restriction. Aging (Milano) ; – Sohal RS, Weindruch R.

Oxidative stress, caloric restriction, and aging. Science. The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary and pharmacological anti-aging interventions. Frontiers Research Topic E-book. Frontiers. Oxidative and inflammatory stress have been implicated as major contributors to the aging process.

Dietary Ca reduced both factors in short-term interventions, while milk exerted a greater effect than supplemental Ca. In this work, we examined the effects of life-long supplemental and dairy calcium on lifespan and life-span related biomarkers in aP2-agouti transgenic (model of diet-induced.

Caloric Restriction Slows Signs of Aging in Humans and the other remained on a regular diet. f by-products of metabolism accelerate aging processes, calorie restriction sustained over several years may help to decrease risk for chronic .Modeling aging and age-related pathologies presents a substantial analytical challenge given the complexity of gene–environment influences and interactions operating on an individual.

A top-down systems approach is used to model the effects of lifelong caloric restriction, which is known to extend life span in several animal models.

The metabolic phenotypes of caloric-restricted (CR; n = Delayed aging by caloric restriction in rhesus monkeys. Caloric restriction is the only environmental intervention that repeatedly and strongly increases maximum lifespan and delays biological aging in laboratory rodents the last 20 years, astonishing progress has been made in defining longevity pathways and identifying factors that contribute to age-related changes in short lived.